Welcome to the Human Adipose Tissue Vascular Cell Atlas Database (Beta Version)

We are delighted to introduce you to the Human Adipose Tissue Vascular Cell Atlas database, which complements the manuscript “Defining the Vascular Niche of Human Adipose Tissue Across Metabolic Conditions.” This database integrates seven publicly available single-cell and single-nucleus RNA sequencing datasets with our in-house generated dataset, which comprises 36% of all cells and 63% of all vascular cells from human subcutaneous adipose tissue.

Designed to be user-friendly for both non-bioinformatician biomedical researchers and bioinformaticians, this database allows for extensive data mining. Bioinformaticians can also download data matrices used to generate the atlas.

This resource is invaluable for generating hypotheses for both vascular and adipose tissue biologists. It enhances our understanding of the functional heterogeneity within the adipose tissue vascular niche, a specialized compartment in the stromal vascular fraction of adipose tissue.

The database includes three datasets:

1. General Annotation of the Human Adipose Tissue Atlas (Dataset 1): Provides an overall view of the human adipose tissue atlas.

2. Characterization of the Vascular Niche (Dataset 2): Offers a detailed analysis of cells within the vascular niche.

3. Characterization of Sub-endothelial Cells (Dataset 3): Presents an in-depth study of a newly identified heterogeneous population of endothelial cells.

Researchers are encouraged to use this interface for data mining. The data matrices utilized in the manuscript will be available for download upon its publication.

We hope you find this database a valuable tool in your research.