Introduction

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Please cite the PD spatial database as:

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Gene Summary


            

Differential expressed genes in different time points compared to sham

* Wilcoxon Rank Sum test were used to identify differentially expressed genes between two groups of cells
* pct: The percentage of cells where the gene detected in the group
* avg_log2FC: log fold-chage of the average expression between the two groups.
* p_val_adj: Adjusted p-value, based on bonferroni correction using all genes in the dataset

Spatial gene expression: Spatial plot

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Spatial geneset score: Spatial plot

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Cell information vs gene expression on reduced dimensions

In this tab, users can visualise both cell information and gene expression side-by-side on low-dimensional representions.

Dimension Reduction

Cell information

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Cell numbers / statistics

Gene expression

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Cell information vs cell information on dimension reduction

In this tab, users can visualise two cell informations side-by-side on low-dimensional representions.

Dimension Reduction

Cell information 1

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Cell information 2

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Gene expression vs gene expression on dimension reduction

In this tab, users can visualise two gene expressions side-by-side on low-dimensional representions.

Dimension Reduction

Gene expression 1

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Gene expression 2

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Coexpression of two genes on reduced dimensions

In this tab, users can visualise the coexpression of two genes on low-dimensional representions.

Dimension Reduction

Gene Expression

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Cell information / gene expression violin plot / box plot

In this tab, users can visualise the gene expression or continuous cell information (e.g. Number of UMIs / module score) across groups of cells (e.g. libary / clusters).



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Proportion / cell numbers across different cell information

In this tab, users can visualise the composition of single cells based on one discrete cell information across another discrete cell information. Usage examples include the library or cellcycle composition across clusters.



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Gene expression bubbleplot / heatmap

In this tab, users can visualise the gene expression patterns of multiple genes grouped by categorical cell information (e.g. library / cluster).
The normalised expression are averaged, log-transformed and then plotted.




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GeneSet Score violin plot / box plot

In this tab, users can visualise a total of 24604 GeneSet score from MsigDB across groups of cells (e.g. libary / clusters).



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Created by DREAMlab, Department of Biomedicine, Aarhus University

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